For you if you live with chronic inflammation, autoimmune-like flares, widening allergies, or fatigue that lingered after an illness. You get a PDF report built around one short, ranked list of what to eat, add, and avoid. You need the raw DNA file you already have from 23andMe, Ancestry, MyHeritage, or another DNA service. No new test. Private by design. The report runs in your browser. Your DNA is never uploaded or stored. Ready in 3 to 10 minutes, with a 14-day refund if you have not started generating it. Get a free example report before you buy If you have cut out foods and added supplements for inflammation and still feel stuck, this report looks at how your genes push on your immune balance. This report reads the genes behind your immune balance and suggests foods and nutrients for your variants. It is for people living with inflammation that keeps flaring, autoimmune-like symptoms, allergies that keep widening, or fatigue that never fully lifted after an illness. Your immune system relies on coordinating cells called T helper cells, and each type has a different job. Th1 cells lead the attack on viruses and bacteria. Th17 cells fight bacteria and fungi and drive strong inflammation. Th2 cells support antibody production and tissue repair, and when they run too hot they are tied to allergies and asthma. Regulatory T cells, often called Tregs, calm the response down once a threat has passed and help keep it from turning on your own tissue. Immune polarization means the balance tipping toward one of these modes and staying there. Your genes are one of the forces that push it, alongside infections, food, mold, toxins, and body weight. The same food or supplement can be recommended for one immune pathway and flagged to avoid for another. Green tea is one example in this report. So which suggestions apply depends on your own variants. The report reads 78 genes across immune signaling and the nutrient systems behind it, looks gene by gene at the pathways that shape that balance, and ranks food-first suggestions for what it finds. Why the same anti-inflammatory plan helps one person and not another Three examples from this report: IL-10 and switching inflammation off. IL-10 is a messenger that tells the immune system to stand down and helps build regulatory T cells. In lab tests, a variant in its control region was linked to lower IL-10 production, which may leave inflammation running longer. Fiber feeds gut bacteria that make a fatty acid called butyrate, and in a study in mice, butyrate helped form regulatory T cells in the gut. Depending on your variants, the report pairs IL-10 with fiber, garlic, cinnamon, exercise, and meditation. TNF-alpha and the Western diet. TNF-alpha is a potent inflammatory messenger. An uncommon TNF-alpha variant made the gene much more active in lab tests, and the report links it to higher inflammation. For this gene the report recommends a Mediterranean-style diet rich in oily fish and fiber, plus foods such as raw crushed garlic, broccoli sprouts, Brazil nuts, and oysters, and flags a Western diet high in saturated fat and refined carbohydrate as raising TNF-alpha. GC, CYP2R1, VDR and vitamin D. In human immune cells studied in the lab, active vitamin D turned down inflammatory messengers and pushed T cells toward the calming, regulatory role. A study of nearly 34,000 people of European descent linked lower vitamin D levels to common variants in GC, which carries vitamin D in the blood, and near CYP2R1, which starts activating it. VDR is the receptor your cells use to respond to vitamin D. The report names sunlight and oily fish as main sources and ties any supplement dose to a blood test with your doctor. Those are three of the mechanisms. The report covers 78 genes across eight areas. What the report analyzes The attack side: Th1 and Th17. How strongly you mount the inflammatory response to infection, and whether it tends to overshoot (IFNG, IL-12B, IL-17A, IL-17RA, TNF-alpha, IL-6, JAK2, STAT3). Innate alarms and the inflammasome. The first-line alarms for infection and damage, including NLRP3, a switch inside cells that can keep inflammation cycling (NLRP3, IL-1B, NFKB1, IRF7, HIF1A, DPP9, CD209). The allergy side: Th2 and mast cells. The messengers behind antibodies, tissue repair, and allergic inflammation, plus the mast cell's IgE receptor (IL-4, IL-4R, IL-5, IL-13, IL-33, FCER1A). Switching inflammation off. How well your body winds a response down, through IL-10 and vitamin D (IL-10, VDR, GC, CYP2R1). Methylation and B vitamins. Which forms of folate, B12, B2, and B6 the report suggests for your variants (MTHFR, MTHFS, MTHFD1, DHFR, SLC19A1, MTR, MTRR, PEMT, BHMT, CBS, COMT, NBPF3). Histamine and detoxification. How you clear histamine and process compounds from food, the environment, and medicines (AOC1/DAO, HNMT, MAOA, MAOB, ALDH2, FMO3, CYP1A2, NAT1, NAT2, CPS1). Vitamin A, iron, and the gut. How you activate vitamin A, handle iron, digest lactose, and process oxalate and uric acid (BCO1, HFE, TF, TMPRSS6, FUT2, LCT, AGXT, GRHPR, HOGA1, SPP1, SLC2A9, ABCG2). Dietary and metabolic genetics. How your body processes fat, cholesterol, and carbohydrate, and the eating pattern the report suggests for your variants (APOE4, FADS1, FADS2, PPARG, PPARA, ADIPOQ, CETP, LIPC, FTO, LEPR, ACE, and more). What you get Every Noorns report follows the same structure, built to cut through overwhelm and point you to action: A Recommendations Summary. A ranked list of foods, nutrients, and lifestyle factors scored by the combined strength of your genetic signal. The place to start. A Conflicts section. Where genes pull in opposite directions on the same intervention, both scores are shown so you and your practitioner can make an informed call. Gene-by-gene pages. Plain-English explanations of every gene, your specific variants, and the targeted changes tied to each one. A Science Deep Dive. The biology of the innate and adaptive immune system, how T helper cells choose their role, and why inflammation sometimes fails to resolve, for when you or your practitioner want to understand the mechanisms. Who it is for Beyond the symptoms named at the top, this report suits people with a diagnosis who want a nutrition plan for their care team, and practitioners designing a protocol. It shares most of its genes with the MCAS and Histamine Report and adds 14 more, covering the infection-fighting Th1 and Th17 side, first-line alarms such as NLRP3, and IL-10. If mast cell reactions and histamine are your main concern, choose the MCAS and Histamine Report, which adds three genes for mast cell growth and histamine production. Your DNA file never leaves your computer When you generate this report, the analysis runs entirely inside your own web browser, on your own device. We do not upload your DNA. We do not store it. We cannot read it. Privacy is enforced by architecture, not by a policy you have to trust. How it works Buy the report. You get a sign-in link by email. There is no password to remember. Add your DNA file. Select the raw data file you already have from 23andMe, Ancestry, MyHeritage, or another DNA service. It is read on your computer and never sent to us. Generate and save. The analysis takes three to ten minutes in your browser, then hands you a PDF to keep. Keep the tab open while it runs. A note on medical care This report is education about your genes and your nutrition. It does not diagnose an immune condition or replace your blood tests. Talk to your doctor before you start a supplement or change a medication.
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